Smart Diagnosis and Early Intervention in PCOS: A Deep Learning Approach to Women’s Reproductive Health

Polycystic Ovary Syndrome (PCOS) is a widespread disorder in women of reproductive age, characterized by a hormonal imbalance, irregular periods, and multiple ovarian cysts. Infertility, metabolic syndrome, and cardiovascular risks are long-term complications that make early detection essential. In this paper, we design a powerful framework based on transfer learning utilizing DenseNet201 and ResNet50 for classifying ovarian ultrasound images. The model was trained on an online dataset containing 3856 ultrasound images of cyst-infected and non-infected patients. Each ultrasound frame was resized to 224×224 pixels and encoded with precise pathological indicators. The MixUp and CutMix augmentation strategies were used to improve generalization, yielding a peak validation accuracy of 99.80% by Densenet201 and a validation loss of 0.617 with alpha values of 0.25 and 0.4, respectively. We evaluated the model’s interpretability using leading Explainable AI (XAI) approaches such as SHAP, Grad-CAM, and LIME, reasoning with and presenting explicit visual reasons for the model’s behaviors, therefore increasing the model’s transparency. This study proposes an automated system for medical picture diagnosis that may be used effectively and confidently in clinical practice.