An Interview and Meta-Review of Transformatics Introductory Lecture of 3rd FEB 2026

A video mini-lecture on the new mathematical theory of transformatics, as applied to basic sequence analysis was delivered on 3rd FEB, 2026 by inventor of the theory and also principal investigator on the Transforming Executable Alphabet (TEA) computer programming language project — currently one of the best examples of how transformatics can be applied in practice. The lecture was the first to be delivered explicitly for the purpose of introducing transformatics to new audiences, and it happens to have come at a time when the most critically important work on formalizing Transformatics — the “Transformatics 101″ mini-thesis, a review and distillation of all earlier work underlying transformatics, is undergoing further revision, and is also being integrated into an upcoming book on applying transformatics in genetics (slated for 2026). However, not everyone coming to transformatics has fair footing in the associated background theory and ideas, and thus this necessary paper, that is actually in the form of an interview, in which I respond to 8 important problems raised by members in the audience concerning that introductory lecture, especially touching on; the notation used in transformatics, the important matter of different kinds of symbol sets, the Anagram Distance Measure (ADM) introduced in the lecture, and what lies ahead beyond just the ADM for interested students and researchers. The material has been presented almost verbatim — with some questions being presented in the native languages (Ganda/Luganda and Cwezi/Runyakitara) as they first came to us — all based on the points solicited from community members since the lecture first went online, and the answers are then augmented with sufficient references to existing transformatics literature to help galvanize the discussion and make this paper serve as an authoritative future reference too.