SCONE: A Practical, Constraint-Aware Plug-in for Latent Encoding in Learned DNA Storage
arXiv:2602.06157v1 Announce Type: new Abstract: DNA storage has matured from concept to practical stage, yet its integration with neural compression pipelines remains inefficient. Early DNA encoders applied redundancy-heavy constraint layers atop raw binary data – workable but primitive. Recent neural codecs compress data into learned latent representations with rich statistical structure, yet still convert these latents to DNA via naive binary-to-quaternary transcoding, discarding the entropy model’s optimization. This mismatch undermines compression efficiency and complicates the encoding stack. A […]