January 2026

Datasette 1.0a24 New Datasette alpha this morning. Key new features: Datasette’s Request object can now handle multipart/form-data file uploads via the new await request.form(files=True) method. I plan to use this for a datasette-files plugin to support attaching files to rows of data. The recommended development environment for hacking on Datasette itself now uses uv. Crucially, you can clone Datasette and run uv run pytest to run the tests without needing to manually create a virtual environment or install […]

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Catastrophic forgetting in continual learning is often measured at the performance or last-layer representation level, overlooking the underlying mechanisms. We introduce a mechanistic framework that offers a geometric interpretation of catastrophic forgetting as the result of transformations to the encoding of individual features. These transformations can lead to forgetting by reducing the allocated capacity of features (worse representation) and disrupting their readout by downstream computations. Analysis of a tractable model formalizes this view, allowing us to identify best- […]

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Imbalanced Domain Generalization (IDG) focuses on mitigating both domain and label shifts, both of which fundamentally shape the model’s decision boundaries, particularly under heterogeneous long-tailed distributions across domains. Despite its practical significance, it remains underexplored, primarily due to the technical complexity of handling their entanglement and the paucity of theoretical foundations. In this paper, we begin by theoretically establishing the generalization bound for IDG, highlighting the role of posterior discrepancy and decision margin. This bound motivates us to […]

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Generative models for 3D molecular conformations must respect Euclidean symmetries and concentrate probability mass on thermodynamically favorable, mechanically stable structures. However, E(3)-equivariant diffusion models often reproduce biases from semi-empirical training data rather than capturing the equilibrium distribution of a high-fidelity Hamiltonian. While physics-based guidance can correct this, it faces two computational bottlenecks: expensive quantum-chemical evaluations (e.g., DFT) and the need to repeat such queries at every sampling step. We present Elign, a post-training framework that amortizes both costs. […]

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Imitation learning has achieved remarkable success in robotic manipulation, yet its application to surgical robotics remains challenging due to data scarcity, constrained workspaces, and the need for an exceptional level of safety and predictability. We present a supervised Mixture-of-Experts (MoE) architecture designed for phase-structured surgical manipulation tasks, which can be added on top of any autonomous policy. Unlike prior surgical robot learning approaches that rely on multi-camera setups or thousands of demonstrations, we show that a lightweight action […]

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Medical multimodal learning faces significant challenges with missing modalities prevalent in clinical practice. Existing approaches assume equal contribution of modality and random missing patterns, neglecting inherent uncertainty in medical data acquisition. In this regard, we propose the Aleatoric Uncertainty Modeling (AUM) that explicitly quantifies unimodal aleatoric uncertainty to address missing modalities. Specifically, AUM models each unimodal representation as a multivariate Gaussian distribution to capture aleatoric uncertainty and enable principled modality reliability quantification. To adaptively aggregate captured information, we […]

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Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from multiple sources, which poses significant challenges for medical multimodal representation learning. Existing approaches typically focus on effective multimodal fusion, neglecting inherent biased features that affect the generalization ability. To address these challenges, we propose a Dual-Stream Feature Decorrelation Framework that identifies and handles the biases through structural causal analysis introduced by […]

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Global air quality forecasting grapples with extreme spatial heterogeneity and the poor generalization of existing transductive models to unseen regions. To tackle this, we propose OmniAir, a semantic topology learning framework tailored for global station-level prediction. By encoding invariant physical environmental attributes into generalizable station identities and dynamically constructing adaptive sparse topologies, our approach effectively captures long-range non-Euclidean correlations and physical diffusion patterns across unevenly distributed global networks. We further curate WorldAir, a massive dataset covering over 7,800 […]

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Overparameterized models have recently challenged conventional learning theory by exhibiting improved generalization beyond the interpolation limit, a phenomenon known as benign overfitting. This work introduces Adaptive Benign Overfitting (ABO), extending the recursive least-squares (RLS) framework to this regime through a numerically stable formulation based on orthogonal-triangular updates. A QR-based exponentially weighted RLS (QR-EWRLS) algorithm is introduced, combining random Fourier feature mappings with forgetting-factor regularization to enable online adaptation under non-stationary conditions. The orthogonal decomposition prevents the numerical divergence […]

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